Mercury intoxication in a 2-year-old girl

Mercury intoxication in a 2-year-old girl_and others

Pediatr Nephrol. 2007 Jun;22(6):903-6. Epub 2007 Feb 20.

Mercury intoxication in a 2-year-old girl: a diagnostic challenge for the physician.

Michaeli-Yossef Y, Berkovitch M, Goldman M.

Source

Department of Pediatrics, Assaf Harofeh Medical Center, Zerifin, 70300, Israel.

Abstract

A 2-year-old girl presented with hypertension, anorexia and vomiting, restlessness, insomnia and acrodynia. Her blood pressure upon arrival was 145/98 mmHg. Ultrasound of the abdomen, CT scan of chest, abdomen and pelvis, and echocardiogram, were normal. Urinary levels of catecholamines were elevated, urine level of mercury was found to be high (33.2 microg/g creatinine), although blood level was normal (>0.5 microg/dl, reference value 0-4 microg/dl). Following a 1-month course of oral treatment with dimercaptosuccinic acid (DMSA) the child's symptoms and signs resolved, and urinary mercury and catecholamines levels normalized. Mercury intoxication should be suspected in a patient with severe hypertension, personality changes and acrodynia. Normal blood levels of mercury do not exclude this diagnosis, and catecholamine levels may serve as a surrogate marker for confirmation of the diagnosis and to evaluate response to treatment.

PMID:

17310361

[PubMed - indexed for MEDLINE]

Acta Paediatr. 2001 May;90(5):593-4.

Familial mercury intoxication presenting with cardiovascular abnormalities and acrodynia.

Laurans M, Brouard J, Arion A, Kauffmann D, Duhamel JF.

PMID:

11430728

[PubMed - indexed for MEDLINE]

Pediatr Dermatol. 2012 Mar-Apr;29(2):199-201. doi: 10.1111/j.1525-1470.2012.01737.x.

Acrodynia and hypertension in a young girl secondary to elemental mercury toxicity acquired in the home.

Mercer JJ, Bercovitch L, Muglia JJ.

Source

Department of Dermatology, Warren Alpert Medical School, Brown University, Providence, Rhode Island 02903, USA.

Abstract

Acrodynia, also known as pink disease, erythredema polyneuropathy, Feer syndrome, and raw-beef hands and feet, is thought to be a toxic reaction to elemental mercury and less commonly to organic and inorganic forms. Occurring commonly in the early 20th century, acrodynia is now a seemingly extinct disease in the modern world because of regulations to eliminate mercury from personal care products, household items, medications, and vaccinations. We present a case of a 3-year-old girl with acrodynia secondary to toxic exposure to elemental mercury in the home environment.

PMID:

22409470

[PubMed - indexed for MEDLINE]

Rev Esp Pediatr. 1962 May-Jun; 18:241-64.

[Akrodynie (Selter-Swift-Feer Krankheit). I].

[Artikel in Spanisch]

RUIZ COMPANY S , Peset REIG R , LLOPIS LLOMBART R .

PMID:

13983249

[PubMed - für MEDLINE indexiert]

MeSH AGB

[Ein Beitrag von Selter-Feer-Swift-Krankheit].

[Artikel in Englisch]

UFLACKER H .

Kinderarztl Prax. 1.957 May; 25 (5) :210-5.

PMID:

13450105

[PubMed - für MEDLINE indexiert]

Tidsskr Nor Laegeforen. 1959 15. September; 79:1061-3.

[Akrodynie. Selter-Swift-Feer Krankheit, pink disease, dermatopolyneuritis: Umfrage und Kasuistiken].

[Artikel in der norwegischen]

Kringlen E .

PMID:

14412023

[PubMed - für MEDLINE indexiert]

Med J Aust. 1951 10. März; 1 (10) :353-62.

Rosa Krankheit: die Manifestation bei älteren Kindern und die Schätzung des Blutes Adrenalin Inhalt.

Tidsskr Nor Laegeforen. 1959 15. September; 79:1061-3.

[Akrodynie. Selter-Swift-Feer Krankheit, pink disease, dermatopolyneuritis: Umfrage und Kasuistiken].

[Artikel in der norwegischen]

Kringlen E .

PMID:

14412023

[PubMed - für MEDLINE indexiert]

Ned Tijdschr Geneeskd. 1951 3. Februar; 95 (5) :378-82.

[Quecksilberoxydul Vergiftung als Ursache acrodynia].

[Artikel in Undetermined Sprache]

BAKX CJ , Lingeman J , PETERS HJ .

Arch Pediatr Fr. 1951; 8 (3) :311-2.

[A tödlicher Fall von Verstümmelung acrodynia in einem 5-jährigen Kind mit einem mercurial Derivat behandelt].

[Artikel in Undetermined Sprache]

Corcos A , STAM'RAD M , ABITBOL S .

PMID:

14830322

[PubMed - für MEDLINE indexiert]

Ugeskr Laeger. 1950 29. Juni; 112 (26) :925-8.

[Akrodynie, eine Überprüfung und Bericht über einen Fall mit Quecksilber im Urin, nach der Behandlung mit Dimercaptopropanol geheilt].