Child with elemental mercury poisoning and unusual brain MRI findings



Abbaslou P <> , Zaman T <> .

Pediatrics Department, Children Medical Center, Tehran University of Medical Sciences, Tehran, Iran.

Clin Toxicol (Phila). 2006;44(1):85-8.



Mercury vapor poisoning is a serious and potentially fatal problem. Neurological manifestations involving the central nervous system are seen with chronic mercury intoxication. We present the case of a 10-year-old child who demonstrated acrodynia, seizures, and visual impairment following 20 days of exposure to elemental mercury at home. The initial blood mercury concentration was 27.7 microg/L (normal <2 microg/L) and the initial 24-hour urine mercury concentration was 34.4 microg/L (normal =10 microg/L). After 9 months of treatment with D-penicillamine, the patient's clinical condition, biochemical laboratory parameters, and mercury concentrations all returned to normal. The T2-weighted MRI images of the patient's brain initially showed multiple hyperintense lesions in cerebral white matter, left globus pallidus, and putamen, which also improved.


     PMID: 16496500 [PubMed - indexed for MEDLINE]